Erectile dysfunction & Gender Identity disorder Essay

Erectile dysfunction & Gender Identity disorder - Essay Example As an erection is so intrinsically tied to masculinity, not being able to achieve one often attacks a man’s sense of his own man-hood. He feels shame and guilt, which often instigates further issues in achieving an erection. In this particular case, a differential diagnosis is helpful because the inability to achieve an erection is caused by a myriad of factors, ranging from daily routine, to physical ailments, and to psychological problems. In creating a list of these three areas, doctors are able to ascertain which area, or what combination of factors is causing the problem. Understanding the root of the problem, which is frequently caused by issues outside of the man’s sexual life, will enable doctors to create an appropriate treatment to rectify the problem. This treatment may take the form of a healthier lifestyle, which involves limiting smoking, drinking, eating unhealthy foods, recreational drug use, lack of sleep, etc. These issues may also contribute to physic al ailments which are contributing to the problem, such as obesity. Finally, the doctor can address the psychological problems involved in the disorder, including feelings of self worth, a possible history of sexual abuse, stress at work, and marital and familial problems. The video included two men, both of which were Caucasian and, presumably, from the middle class. Historically, White men have not had to explain their sexuality, nor have they experienced attacks on their sexuality in terms of being defined as barbaric, as seen in the depiction of African males, or as too effeminate, as seen in the depiction of Asian males. In this regard, White males may be more inclined to visit a doctor and receive the necessary treatment to cure the problem. However, the significance of machismo or the centrality of the male in gender relations may prevent a non-White

The Acquisition of Walls With Polka and the Acquisition of Adobe With Research Paper

The Acquisition of Walls With Polka and the Acquisition of Adobe With Macromedia - Research Paper Example Acquisition is the purchase of one company by another company. For successful acquisition deal, company should take enough data about the market position and market performance of acquiring company. Because of not collecting enough data, 50% of acquisition deals are unsuccessful. Here we represent the two examples of successful acquisition deals. Acquisition of Wall’s with Polka In 1993, the administration of Lever Brothers formulated a team to search for business potential of Ice Cream in Pakistan. This team went back with the result that there is a lot of potential of Ice Cream business in Pakistan. So they decided to launch Wall’s ice cream in Pakistan. Wall’s is the biggest ice cream manufacturers in the world and second to it is Nestle. The administration of Wall’s wanted to enter in the market through acquisition strategy. They wanted to acquire Polka which was the established local brand and was representing the only national ice cream business in P akistan. They wanted to save time by acquiring Polka which was needed to capture the market. In 1994 Lever Brothers tried to acquire Polka ice cream for US$ 600 million but Polka refused the bid and they demand one billion rupees. But Wall’s established an ice cream factory in eleven months and did not acquire Polka (LePage, 2007). In February 1995, Wall’s launched with twelve products. After the launching they gave tremendous services and Polka loosed its market share. At this time Polka approached Wall’s to sell itself but now Wall’s had done all the hard work which they did not initially want to do by acquiring Polka. The administration of Polka spread a rumor that Nestle is coming through Polka which Wall’s did not want because Nestle is the biggest competitor of Wall’s. So Wall’s purchased Polka in 1997. The Strengths of the acquisition of Wall’s with Polka. After the acquisition they are working together for many years. O n Polka packaging there is a brand mark of Wall’s ice cream. The acquisition of Wall’s with Polka enhances the resource strengths and competitive capabilities of these companies in this way. 1. This acquisition made Wall’s the unchallenged leader and now the sale of Wall’s 85% and all other brands like Yummy, Hico and Igloo have sale with single digit. Omore is another emerging brand but its sale cannot compete Walls. 2. The Wall’s emerged as â€Å"Impulse Brand† 3. Unilever is also the most reliable brand in the country and through this acquisition Polka also saves itself from the tough competition and also realize that it was facing loss in market share before the acquisition 4. If Nestle was approached Polka then it would become biggest threat for Wall’s as Polka was the only local brand and also most familiar brand for the people of country. The Wall’s save itself from tough competition through acquisition. Acquisition of A dobe with Macromedia Adobe Systems Incorporated is an American multinational computer software company and it was founded in 1982 by John Warnock (Adobe’, 2012). The company has focused upon the creation of multimedia and creativity software products. In 2005, Adobe acquired its former competitor Macromedia.

Ocular Manifestations of Mucopolysacchridosis

Ocular Manifestations of Mucopolysacchridosis Ocular manifestations of mucopolysacchridosis Praddep Sagar Arsikere, Pradeep Venkatesh, Yog Raj Sharma Mucopolysaccharidoses  (MPS)  are a group of disorders caused by  the  inherited deficiency of lysosomal enzymes involved in  the  metabolism of glycosaminoglycan  (GAG),  resulting in  the  widespread intracellular and extracellular accumulation of  GAG.  > Type Gene Deficient enzyme GAG deposited IInheritance  pattern Hurler syndrome (MPS I-H) IDUA (4p16.3) Alpha-L-iduronidase Dermatan sulfate, heparan sulfate AR Hurler-Scheie syndrome  (MPS I-H/S) IDUA (4p16.3) Alpha-L-iduronidase Dermatan sulfate, heparan sulfate AR Scheie syndrome (MPS I-S) IDUA (4p16.3) Alpha-L-iduronidase Dermatan sulfate, heparan sulfate AR Hunter syndrome, severe (MPS II-A) IDS (Xq28) Iduronate sulfatase Dermatan sulfate, heparan sulfate XR Hunter syndrome, mild (MPS II-B) IDS (Xq28) Iduronate  sulfatase Dermatan sulfate, heparan sulfate XR Sanfilippo syndrome A (MPS III-A) SGSH (17q25.3) Heparan  N-sulfatase Heparan sulfate AR Sanfilippo syndrome B (MPS III-B) NAGLU (17q21) Alpha-N-acetylglucosaminidase Heparan sulfate AR Sanfilippo syndrome C (MPS III-C) HGSNAT (8p11.1) Heparan-alpha-glucosaminide Nacetyltransferase Heparan sulfate AR Sanfilippo syndrome D (MPS III-D) GNS (12q14) N-acetyl alpha-glucosamine-6-sulfatase Heparan sulfate AR Morquio syndrome A (MPS IV-A) GALNS (16q24.3) N-acetylgalactosamine 6-sulfatase Keratan sulfate AR Morquio syndrome B (MPS IV-B) GLB1 (3p21.33) Beta-galactosidase Keratan sulfate AR Maroteaux-Lamy syndrome (MPS VI) ARSB (5q14.1) Arylsulfatase B Dermatan sulfate AR Sly syndrome (MPS VII) GUSB (7q21.11) Beta-glucuronidase Dermatan sulfate, heparan sulfate, Chondroitin sulfate AR Natowicz syndrome  (MPS IX) HYAL1 (3p21) Hyaluronidase AR Ocular manifestations 1. Ocular adnexa Eyelid thickening  occurs  due to  the  accumulation of  GAG. Hypertelorism has been reported in MPS types  III,  Ã‚  II and  Ã‚  VII. Pseudoproptosis due to shallow orbit has been reported in a patient with MPS VI  and MPS II. 2. Cornea The extracellular matrix of corneal stroma contains dermatan sulfate and keratan sulfate in equal proportion. Both dermatan sulfate and keratan sulfate are synthesized by stromal keratocytes. Dermatan sulfate proteoglycans are involved in  the  control of interfibrillar spacing and in  the  lamellar adhesion of corneal collagens. Keratan sulfate proteoglycans are involved in the regulation of collagen fibril diameter. Mainly,  epithelial cells synthesize heparan sulfate proteoglycans,  and they are minor components of cornea. Since dermatan sulfate and keratan sulfate are the major GAGs in  the  corneal stroma, corneal involvement is mainly seen in MPS types  I, IV, VI and VII. In corneas of patients with MPS,  the  excessive accumulation of dermatan sulfate or keratan sulfate in the form of vacuoles can be seen in epithelial cells, keratocytes, histiocytes and extracellular matrix. An increase in  the  mean fibril diameter of collagen and  an  increase in fibril spacing  are  noted in the corneal stroma of patients with MPS I. These structural alterations in collagen fibrils may contribute to light scattering. But the corneal clouding is mainly due to  the  accumulation of GAGs in all the layers of cornea with enlarged stromal keratocytes. Corneal involvement is typically not seen in type III, as the metabolism of heparan sulfate is impaired in type III and heparan sulfate is not synthesized by stromal keratocytes. Symptoms include gradually progressive painless diminution of visual acuity and light intolerance due to scattering of light. In early cases, fine grey punctuate opacities in anterior stroma are visible. In advanced cases,  there is diffuse corneal clouding. Corneal thickness is variable, and it may be increased or normal.  Corneal hysteresis is increased. Corneal  oedema  occurs in cases with  increased intra-ocular  pressure  (IOP). 3.  Optic nerve GAGs  are the major components of  the  extracellular matrix of  the  optic nerve head.  Proteoglycans containing chondritin sulfate and dermatan sulfate are located in lamina cribrosa, supporting tissues of the optic nerve head like septae, pia. Proteoglycans containing heparan sulfate are located in margins of laminar plates of lamina cribrosa.  The  optic nerve involvement can be due to accumulation of  Ã‚  GAG  in  the  extracellular matrix of  the  optic nerve, narrowing of pores in lamina cribrosa, thickening of dura  and  narrowing of bony optic canal  Ã‚  that  leads  to disc  oedema  (pseudopapilloedema). It can also be due to raised intracranial pressure manifesting as true papilloedema.  Long-standing axonal compression or papilloedema  can lead to secondary optic atrophy.  The  accumulation of GAG in ganglion cells of retina can lead to axonal degeneration and optic atrophy. Optic nerve involvement is more commonly seen in types  I, II, VI  and  VII,  as the major  Ã‚  GAGs  in optic nerve and lamina cribrosa are dermatan sulfate and chondritin sulfate. Optic nerve involvement is less with type III,  as heparan sulfate is located in the margins of lamina cribrosa,  and in type IV,  as keratan sulfate is not present in the optic nerve head in human.   4.  Glaucoma The human trabecular meshwork contains chondroitin sulfate, keratan sulfate, heparan sulfate  and  dermatan sulfate.  The  accumulation of  Ã‚  GAG  in the anterior segment structures can lead to  the  narrowing of angle resulting in acute angle closure and chronic angle closure glaucoma. Anterior segment  optical coherence tomography  (OCT)  imaging in mucopolysacchridosis suggests crowded anterior segment and increased corneal thickness in type VI than  in  type I.  The  accumulation of GAG in trabecular cells can lead to features similar to open-angle glaucoma.  The  measurement of IOP by Goldmann applanation tonometer may be falsely high due to increased corneal thickness and corneal hysteresis.  The  visualization of angle by gonioscopy may be compromised due to corneal clouding,  thus posing difficulty in differentiating open angle from closed angle.  The  monitoring of progression and severity of glaucomatous optic neuropathy may be compromised by corneal clouding and disc  oedema. Anterior segment OCT is a valuable tool in  the  assessment of angle, particularly in patients with corneal clouding. Ocular response  Ã‚  analyser  can be used  for the  accurate measurement of IOP in these cases. 5. Retina Heparan sulfate, dermatan sulfate, chondroitin sulfate and hyaluronan are present throughout the retina and choroid. Heparan sulfate is particularly located in  the  basement membrane containing structures, the RNFL and RPE. Keratan sulfate is absent in  the  retina and choroid.  Ã‚  GAGs  are integral components of  the  basement membrane of retinal microvasculature,  and heparan sulfate is the predominant variety. Tapetoretinal degeneration has been reported in MPS types  I,  Ã‚  II,  Ã‚  III and  Ã‚  IV. 6.  Sclera Scleral thickening may lead to  the  uveal effusion syndrome. Suggested Reading 1.  Villas-Boas FS, Fernandes Filho DJ, Acosta AX.  Ocular findings in patients with mucopolysaccharidosis.  Arq Bras Oftalmol  2011;74(6):430–434. 2.  Viestenz A, Shin YS, Viestenz A, Naumann GO.  Ocular  manifestation of  mucopolysaccharidosis I-S (Scheies  syndrome).  Klin Monbl Augenheilkd  2002;219(10):745–748.

Glaciers Essay examples -- Ice Glaciers Essays

Glaciers As many people hear the word glacier they immediately think about the Titanic and how it sank because it ran into a glacier. What many people do not know is the history of glaciers. There are a couple different types of glaciers, for instance the type that the titanic ran into is a Tidewater glacier, which is a glacier that flows in the sea. There are also alpine glaciers which are glaciers that are found in the mountains, and there are Continental glaciers which are associated with the ice ages, and that covers most of the contnents at one time; including Indiana. Glacier ice is the largest amount of fresh water in the world only second to the oceans as the largest reservoir of water total. Glaciers are found on every continent except Australia. Glaciers are more or less permanent bodies of ice and compacted snow that have become deep enough and heavy enough to flow under their own weight. Glaciers require very specific climatic conditions. Glaciers develop where the temperatures are cold enough to allow the snow to accumulate and compacted. Most are found in regions of high snowfall in winter and cool temperatures in summer. These conditions ensure that the snow that accumulates in the winter isn't lost (by melt, evaporation, or calving) during the summer. Such conditions typically prevail in polar and high alpine regions. There are two main types of glaciers: valley glaciers and continental glaciers (Armstrong).   Ã‚  Ã‚  Ã‚  Ã‚   When it comes to the snow lasting ...

Lord Byron Essay

Lord Byron is considered to be one of the most important poet in his time. He was as famous for his personality as he was for his poetry. The way his life affected what he wrote made his poems even better. His works, life, and writing style are what made Lord Byron one of the most important poets of the Romantic Movement. George Gordon Noel Byron (Lord Byron) was born on January 22, 1788 in London, England. His dad, Captain â€Å"Mad Jack† Byron married his mother, Catherine Gordon, for her money. Throughout their marriage he spent away most of her fortune before he died in 1791. When Lord Byron’s father died he was left with nothing. After his father died he seemed to have a long life ahead of him. He had a birth defect that made him walk on his toes for his entire life and his mother was unstable. Lord Byron took out his stress by writing poetry. When he was only eight years old he fell in love. When he turned sixteen years old he was told that the woman he loved was engaged. He became very depressed and felt very ill. In 1798 his granduncle died and Lord Byron inherited his uncles estate. Now that he had some money, he went to Trinity College after spending his time from 1801 to 1805 at Harrow. In 1808, he planned to spend the year with his cousin, George Bettesworth. He was the captain of his own ship and in May of 1808 he died in the Battle of Alvon. So, from 1809 to 1811 Lord Byron spent the years cruising the Mediterranean. The Napoleonic Wars were going on in Europe at this time so he had to avoid most of Europe. During this time Lord Byron’s first book of poetry, Hours of Idleness, was published in 1809. The two-year Mediterranean trip gave him most of the material he wrote about in Childe Harold’s Pilgrimage. These two cantos were the first great successes he had. In 1813 Lord Byron apparently had more than a brother-sister relationship with his half sister Augusta Leigh. She was already the mother of three children. She gave birth to Elizabeth Medora in 1814. Elizabeth was thought by many people to be Lord Byron’s child, but in 1815 he married Anne Isabella Milbanke. They had a child named Ada in the same year, but the marriage did not last and they separated the next year. In 1816 Byron left England when rumors started of his debts. He was never to return back to England in his life. †The only virtue they honor in England is hypocrisy,† (Liukkonen, Petri) he wrote in a letter to his friend when he left England. He settled in Geneva, where he meant Claire Clairmont. She became his mistress, but at the end of summer he moved again. He spent two years working and writing in Italy. â€Å"I was struck by his eyes†¦ I have never in my life seen anything more beautiful or more expressive,† (Liukkonen, Petri) is a quote from a French writer that saw Lord Byron at an opera in Italy. While in Italy he, wrote several poems including Lament of Tasso, Mazeppa, and The Prophecy of Dante. During his stays in Italy he became very interested in drama. He wrote several dramas including The Two Foscari, Sardanapalaus, and many others. In January of 1817, Claire Clairmont gave birth to his daughter Clara Allegra. Lord Byron abandoned his daughter and she died in 1822 with a bad case of typhus fever. In Italy, he risked his life helping a secret group called the Italian Carbonari in 1820 and 1821. In 1824 he decided to take action and move to Greece. He joined a group called the Greek freedom fighters. By this time he was in Missolonghi, Greece. He unfortunately died here on April 19, 1824 of a fever. Lord Byron is the most well known of the famous romantic poets. His poetry had a recurring theme of being romantic. Lord Byron wrote many long romantic poems and some shorter ones in a traditional satirical style of poetry. His poems all varied in their subject matter. A lot of his romantic poems were about the many women he was involved with. An example would be the poem She Walks in Beauty, it is a poem about how beautiful he thought the woman he was in love with was. His poems also were about things he believed in. The poem, The Destruction of Sennacherib, shows that Lord Byron shared his religious views in his poetry. Throughout his travels he went to many places that were inspiration for his poetry. The Lament of Tasso was written when he was in Rome. He visited Tasso’s cell, which inspired him to right the poem. His vary in types of poetry and subject matter helped his poetry stay popular. Lord Byron’s poetry has many connections with what was going on in his life. He first started writing poetry to release the stress of the birth defect that he was born with. His different kinds of poetry were all connected with his life. He was most known for his romantic poetry. In these poems, he wrote about the relationships he had with woman. The places he travelled also influenced his poetry. His travels in Italy got him into drama and that was result of many of his best poems. How religious he was and how much he cared about what was going on around him showed in his life and in his poetry. He wrote about and it was also the reason he chose to move to Greece to help them rise over their rulers by joining the Greek freedom fighters. The connection between his life and his poetry is what made him as popular as he was. Lord Byron was one of the most famous and talented writers of his time. His life, poetry, and the way they were connected are what made him one of the most famous poets of his time. His poetry was an influence on the writing of other poets in his time and continues to influence poets today.

Animal Senses vs Human Senses Essay

Through research I discovered that there are animals that have senses that by far exceed our five human senses. One of the animals would be the bat that we spoke about in class. Bats avoid obstacles and nab insects on the wing by emitting ultrasonic squeaks and interpreting the echo the sound waves make after bouncing off objects in the environment. This is called â€Å"echolocation,† but bats aren’t the only animals that use echolocation. Dolphins also use echolocation to navigate themselves in murky water. Sharks were also discussed in class. Sharks have special cells in their brains that are sensitive to the electrical fields other creatures generate. This ability is so refined in some sharks that they can find fish hiding under sand by the weak electric signals their twitching muscles emit. They pick any electrical signal around them and even the weakest of electrical pulses give them a reason to investigate if its food or not. There are a few animals that we didn’t speak about in class that have senses that far exceed our own. For example Boa constrictors (large snake) have Temperature-sensitive organs located between the eyes and nostrils of boas and pit vipers allow the snakes to sense the body heat of their prey. There is one located on each side of the snakes’ head, so the animals can perceive depth and attack with deadly accuracy even in complete darkness. Snakes in general also have another sense that is similar in a way to ours. Snakes have a forked tongue that is used to sniff its surroundings. Snakes use their tongues to collect particles wafting in the air. The coated tongue is then dipped into special pits in the roofs of the snake’s mouth, called Jacobson’s organs. There, the odors get processed and translated into electrical signals that are sent to the brain. Humans use their eyes to see their surroundings but the object in front of them is processed almost like our eyes take a picture and send the image to the brain they can recognize the object. The final one would be the Migratory birds. Birds that migrate can use the Earth’s magnetic field to stay their course during long flights. Scientists still aren’t sure how they do it, but one recent study suggests birds might have a form of synesthesia (a condition in which one sense (for example, hearing) is simultaneously perceived as if by one or more additional senses such as sight) that lets them â€Å"see† the planet’s magnetic lines as patterns of color or light that is overlaid on their visual surroundings. Humans must rely on familiar landmarks or the sun’s position to locate north, and there are a lot of humans that can barely manage to do that.